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1 article(s) from Tomašić Paić, Ana

Phenanthridine–pyrene conjugates as fluorescent probes for DNA/RNA and an inactive mutant of dipeptidyl peptidase enzyme

Josipa Matić,
Tana Tandarić,
Marijana Radić Stojković,
Filip Šupljika,
Zrinka Karačić,
Ana Tomašić Paić,
Lucija Horvat,
Robert Vianello and
Lidija-Marija Tumir

Beilstein J. Org. Chem. 2023, 19, 550–565, doi:10.3762/bjoc.19.40

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Scheme 1: Novel pyrene–phenanthridine conjugates Phen-Py-1 (longer, flexible linker) and Phen-Py-2 (shorter, ...

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Scheme 2: Synthesis of Phen-Py-1 and Phen-Py-2 by amide formation; Reagents and conditions: 1. TFA–H₂O mixtur...

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Figure 1: 2D (left) and 3D (right) representation of fluorescence emission spectra of Phen-Py-1 (c = 2 × 10⁻⁶...

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Figure 2: Most representative structures of the conjugates Phen-Py-1 and Phen-Py-2 at different pH conditions...

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Figure 3: UV–vis titration of Phen-Py-1 with ct-DNA,; changes in the UV–vis spectra of Phen-Py-1 at λ = 350 n...

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Figure 4: . Experimental (■) and calculated (–) (by Scatchard equation Table 2) fluorescence intensities of compound ...

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Figure 5: Comparison of spectra of DNA-dye complex (r = 0.5, black) and sum of DNA and dye spectra (red) of a...

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Figure 6: Fluorimetric titration of Phen-Py-1, λ_exc = 352 nm, c = 1 × 10⁻⁶ mol dm⁻³ with dipeptidyl peptidase...

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Figure 7: A: ITC titration: raw titration data from the experimental injections of human DPP III enzyme mutan...

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Published 26 Apr 2023

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